source : pixabay
Brand & Generic Names
|ATROPINE & PHENOBARBITAL||Donnatal|
|ATROPINE, HYOSCYAMINE,||Donnatal Extentabs|
|SCOPOLAMINE &||Donnatol No. 2|
|ATROPINE, HYOSCYAMINE,||HYOSCYAMINE &|
|Barophen||Levsin with Phenobarbital|
|Belladenal||Levsinex with Phenobarbital|
|BELLADONNA & AMOBARBITAL||Pheno-Bella|
|BELLADONNA & BUTABARBITAL||Relaxadon|
- Habit forming? Yes
- Prescription needed? Yes
- Available as generic? Some yes, some no
- Drug class: Antispasmodic, anticholinergic, sedative
- Reduces spasms of digestive system, bladder and urethra.
- Reduces anxiety or nervous tension (low dose).
- Relieves insomnia (higher bedtime dose).
DOSAGE & USAGE INFORMATION
- How to take: Tablet, liquid or capsule–Swallow with liquid or food to lessen stomach irritation. If you can’t swallow whole, crumble tablet or open capsule and take with liquid or food.
- Extended-release tablets or capsules– Swallow each dose whole.
- Chewable tablets–Chew well before swallowing.
- Drops–Dilute dose in beverage before swallowing. When to take: At the same times each day. If you forget a dose: Take as soon as you remember up to 2 hours late. If more than 2 hours, wait for next scheduled dose (don’t double this dose). What drug does:
- May partially block nerve impulses at nerve-cell connections.
- Blocks nerve impulses at parasympathetic nerve endings, preventing muscle contractions and gland secretions of organs involved.
- Time lapse before drug works: 15 to 30 minutes.
- Don’t take with: Any other medicines, even over-the-counter drugs such as cough and cold medicines, nose drops, diet pills, laxatives or caffeine, without consulting your doctor.
- SYMPTOMS: Blurred vision, confusion, convulsions, irregular heartbeat, hallucinations, coma.
- WHAT TO DO: Dial 0 (operator) or 911 (emergency) for an ambulance or medical help. Then give first aid immediately.
POSSIBLE ADVERSE REACTIONS OR SIDE EFFECTS
SYMPTOMS WHAT TO DO
- Life-threatening: Unusual excitement, Seek emergency restlessness, fast treatment immediately. heartbeat, breathing difficulty.
- Common: Dry mouth, throat, Discontinue. Call nose; drowsiness; doctor right away. constipation; dizziness; nausea; vomiting; “hangover” effect; depression; confusion.
- Reduced sweating, Continue. Call doctor slurred speech, when convenient. agitation. Infrequent: Difficult urination; Discontinue. Call difficult swallowing; doctor right away. rash or hives; face, lip or eyelid swelling; joint or muscle pain. Rare: Jaundice; unusual Discontinue. Call bruising or bleeding; doctor right away. hives, skin rash; pain in eyes; blurred vision; sore throat, fever, mouth sores; unexplained bleeding or bruising.
WARNINGS & PRECAUTIONS
Don’t take if:
- You are allergic to any barbiturate or any anticholinergic.
- You have porphyria, trouble with stomach bloating, difficulty emptying your bladder completely, narrow-angle glaucoma, severe ulcerative colitis.
Before you start, consult your doctor:
- If you have open-angle glaucoma, angina, chronic bronchitis or asthma, hiatal hernia, liver disease, enlarged prostate, myasthenia gravis, peptic ulcer, epilepsy, kidney or liver damage, anemia, chronic pain.
- If you will have surgery within 2 months, including dental surgery, requiring general or spinal anesthesia. Pregnancy: Risk to unborn child outweighs drug benefits. Don’t use. Infants & children: Use only under doctor’s supervision.
- May cause addiction, anemia, chronic intoxication.
- May lower body temperature, making exposure to cold temperatures hazardous. Skin & sunlight: May cause rash or intensify sunburn in areas exposed to sun or sunlamp.
Driving or hazardous activities:
Don’t drive or pilot aircraft until you learn how medicine affects you. Don’t work around dangerous machinery. Don’t climb ladders or work in high places. Danger increases if you drink alcohol or take medicine affecting alertness and reflexes.
May be unnecessary to finish medicine. Follow doctor’s instructions. If you develop withdrawal symptoms of hallucinations, agitation or sleeplessness after discontinuing, call doctor right away.
Others: Great potential for abuse.
Possible Interaction with Other Drugs
|GENERIC NAME||COMBINED EFFECT|
|Acetaminophen||Possible decreased barbiturate|
|Amantadine||Increased belladonna effect.|
|Antacids||Decreased belladonna effect.|
|Anticonvulsants||Changed seizure patterns.|
|tricyclics (TCA)||oversedation. Avoid.|
|Antihistamines||Dangerous sedation. Avoid.|
|Aspirin||Decreased aspirin effect.|
|Attapulgite||Decreased belladonna effect.|
|Beta-adrenergic||Decreased effects of|
|Carteolol||Increased barbiturate effect.|
|Central nervous||Dangerous sedation. Avoid.|
|Cortisone drugs||Increased internal eye pressure.|
|Decreased cortisone effect.|
|Digitoxin||Decreased digitoxin effect.|
|Doxycycline||Decreased doxycycline effect.|
|Dronabinol||Increased effects of both drugs.|
|Furosemide||Possible orthostatic hypotension.|
|Griseofulvin||Decreased griseofulvin effect.|
|Haloperidol||Increased internal eye pressure.|
|Indapamide||Increased indapamide effect.|
|Ketoconazole||Decreased ketoconazole effect.|
|MAO inhibitors||Increased belladonna and|
|Meperidine||Increased belladonna effect.|
|Methylphenidate||Increased belladonna effect.|
|Metronidazole||Decreased metronidazole effect.|
|Mind-altering drugs||Dangerous sedation. Avoid.|
|Narcotics||Dangerous sedation. Avoid.|
|Nitrates||Increased internal eye pressure.|
|Nizatidine||Increased nizatidine effect.|
|Non-steroidal||Decreased anti-inflammatory effect.|
|Orphenadrine||Increased belladonna effect.|
|Pain relievers||Dangerous sedation. Avoid.|
|Phenothiazines||Increased belladonna effect. Danger|
|Pilocarpine||Loss of pilocarpine effect in|
|supplements||ulcers with oral potassium tablets.|
|Quinidine||Increased belladonna effect.|
|Sedatives||Dangerous sedation. Avoid.|
|Sleep inducers||Dangerous sedation. Avoid.|
|Sotalol||Increased barbiturate effect.|
|Tranquilizers||Dangerous sedation. Avoid.|
|Valproic acid||Increased barbiturate effect.|
|Vitamin C||Decreased belladonna effect. Avoid|
|large doses of vitamin C.|
Possible Interaction with Other Substances
|INTERACTS WITH||COMBINED EFFECT|
|Alcohol:||Possible fatal oversedation. Avoid.|
|Cocaine:||Excessively rapid heartbeat. Avoid.|
|Marijuana:||Drowsiness and dry mouth. Avoid.|
|Tobacco:||Decreased effectiveness of acid|
|reduction in stomach.|
From the Complete Guide to Pediatric Symptoms, Illness & Medications by H. Winter Griffith, M.D. © 1989 The Putnam Berkley Group, Inc.; electronic rights by Medical Data Exchange.